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Mode of action / characterization
Mode of action / characterization
• Viability (MTT, LDH, FACS)
• Cell adhesion, cell proliferation (cell counter, trypan blue exclusion, FACS)
• Cell Metabolism : a unique platform for subrates and enzymatic activity measurement (Citrate synthase, complex I-V, SOD, GS, GCS…)
• Oxidative stress (NO, iNOS, …)
• Cartilage catabolism and anabolism : COLL2.1, COLL1, ACAN, MMP, ADAMTS (qPCR, IF / IHC, WB, ELISA, Multiplex)
• Inflammation : cytokines (WB, ELISA, Multiplex)
Characterization by Omics : genomics (DNA), transcriptomics, proteomics, and metabolomics
Preclinical
Lab facility and Animal facility
In vivo test systems
In vitro test systems
Mode of action / characterization
Biocompatibility studies
Macroscopy and Histology
Mobility / pain platform
Other services
Clinical
Biotesting
Regulatory
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