Macroscopy and Histology


• Macroscopic scoring of joint lesions (synovium, cartilage and bone) 

• Synovial fluid scoring and cytological examination

• Biomechanic (MACH-1)

• Histology (H&E, Saf-O, Red Sirius, toluidin blue)
   – paraffin, cryosection, resin- muscle, cartilage, bone, synovium…
   – scoring following OARSI and ICRS recomendations


OARSI-rgb-logo_2011-(2).jpg                           icrs-logo-(1).jpg  

• Histomorphometry (TRAP, ALP, Von Kossa)

• IHC / IF  (22 markers)
   – anabolic – catabolic- inflammation – muscle fibers determination


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