The goal of this narrative review is to summarize the scientific data available in the literature on soluble biomarkers in animal models of OA.

Published on 07/07/2016

Review of Soluble Biomarkers of Osteoarthritis

A literature search was conducted using the PubMed/ Medline and Scopus databases between February 1995 and December 2015. All original articles, systematic and narrative reviews published in French or in English were considered.
We summarized the data of 69 studies and proposed a classification scheme for OA biomarkers in animal studies, largely inspired by the BIPEDS classification.
Studies about biomarkers and animal models indicate that some markers could be valuable to monitor OA progression and assess therapeutic response in some animal models.



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